Talk:Scrapie

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Wiki Education Foundation-supported course assignment

This article is or was the subject of a Wiki Education Foundation-supported course assignment. Further details are available on the course page. Student editor(s): Cjc345.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 08:48, 17 January 2022 (UTC)[reply]

Untitled

--217.156.106.164 09:40, 21 Mar 2005 (UTC)structure of prions Jakey Ritter Likes the good boys \

Older names?

Since scrapie has been known since 1732 but the word isn't first recorded until 1910, does anybody have an idea what it was known as in the almost two centuries between? — Hippietrail 16:07, 31 January 2006 (UTC)[reply]

It might be interesting to note that the word 'sheep' was a curse word among the Irish who were displaced from their tenement land by their English masters who discovered they could earn more profits from wool production. Irish were also the largest immigrant group to north america and have had much influence on americas venacular. ~~nasr~~ — Preceding unsigned comment added by 68.100.61.25 (talk) 02:27, 14 March 2006‎ (UTC)‎ ex-mr.x, 13 march 2006 — Preceding unsigned comment added by 68.100.61.25 (talk) 02:28, 14 March 2006 (UTC)‎[reply]

What has ex-mr.x's comment got to do with this article, it seems to be about sheep in general! George-E 00:02, 13 May 2007 (UTC)[reply]

WikiProject class rating

This article was automatically assessed because at least one WikiProject had rated the article as stub, and the rating on other projects was brought up to Stub class. BetacommandBot 16:31, 10 November 2007 (UTC)[reply]

incidence?

what is the incidence of scrapie in sheep? is it rare like cjd or more common the article doesn't seem to suggest one way or the other. —Preceding unsigned comment added by 129.67.178.236 (talk) 22:50, 2 June 2008 (UTC)[reply]

The disease is nowhere endemic and comparing it with other disease in the WAHID database [1] seems to indicate that it's a fairly rare disease. It's unusual in that it's mostly limited to europe and the US, while other, far more common animal diseases like foot and mouth disease, are a big problem in third world countries. EverGreg (talk) 08:54, 3 June 2008 (UTC)[reply]

How to tell

i am wondering how you tell that your animal has scerapie — Preceding unsigned comment added by 66.96.67.189 (talk) 03:11, 19 May 2009‎ (UTC)[reply]

The symptoms listed here include a strong urge to scratch against trees and such, as well as a strange gait. There is no fever or loss of appetite. However, a veterinarian will have to make the final diagnosis. EverGreg (talk) 09:02, 19 May 2009 (UTC)[reply]

Alleles

Since going towards the ARR/ARR allele in sheep it has turned out that they are more susceptible to a different kind of scrapie, so it is possible that the VRQ sheep evolved to be resistant to this one. I don't know if this is worth mentioning? —Preceding unsigned comment added by Brionyvet (talk • contribs) 22:08, 9 September 2010 (UTC)[reply]

It surely sounds worth mentioning, at least the susceptibility to the other scrapie. Could you help us with a journal/paper reference on this one? EverGreg (talk) 18:24, 10 September 2010 (UTC)[reply]

Transmission to humans

If you are going to make the claim that scrapie may be transmitted to humans (Creutzfeldt–Jakob disease) please cite references. The information I have found does not support the theory that scrapie is transmitted to humans. This is in reference to changes made by user: 138.251.95.1. (3ternalist01 (talk) 17:58, 4 December 2011 (UTC))[reply]

I would also argue that the information found in the source here is definitely not the information listed in the wikipedia. This sentence is very weird. What is the suggested relationship between scrapie and sporadic CJD? And where is this information in the source? I would like to read this source more closely and determine if there is a better way to explain what is says. If someone has the time please help to edit this sentence. 2600:6C67:6D7F:A084:B965:89CE:EB84:3F2 (talk) 01:01, 30 October 2022 (UTC)[reply]

Potential genetics section

This is a section about the genetics of scrapie. I think it would fit under Transmission and pathogenesis.

Three locations on the prion protein gene have been identified as highly polymorphic and may have an effect on scrapie: codons 136, 154, and 171 (LaPlanche 1992). Codon 154 has not shown any evidence of having a high effect on scrapie susceptibility; however, codons 136 and 171 are thought to control the incubation time of the disease (Goldmann 1991; Goldmann 1990). Codon 171 has been determined to be the major genetic factor in scrapie susceptibility (Clouscard 1995; Westaway 1993).

I will insert citations when it is published. Let me know if anyone has suggested edits or suggested section to put this in. — Preceding unsigned comment added by Cjc345 (talk • contribs) 18:14, 16 October 2018 (UTC)[reply]

Scale and impact need inclusion

This article would benefit from including the scale, longevity, timing, location and pattern of outbreaks, especially major ones. Also, the economic loss, either through infected animals becoming unfit to eat or through preventive culls. Jontel (talk) 16:17, 14 August 2020 (UTC)[reply]